Ivica, J., Kejzar, N., Ho, H. et al. Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization. Nat Struct Mol Biol (2024). https://doi.org/10.1038/s41594-024-01369-5

• Keywords: Synaptic transmission, Structural and Molecular Biology, AMPA glutamate ion channels, Receptor Kinetics

Huang, J., Jaekel, A., van den Boom, J. et al. A modular DNA origami nanocompartment for engineering a cell-free, protein unfolding and degradation pathway. Nat. Nanotechnol. (2024). https://doi.org/10.1038/s41565-024-01738-7

• Keywords: DNA Origami architecture, Bionanotechnology, p97 molecular chaperone, metabolic pathways, multicatalytic function

Calcium oscillations optimize the energetic efficiency of mitochondrial metabolism. Cell Press. doi: https://doi.org/10.1016/j.isci.2024.109078

• Keywords: Mitochondrial efficiency, Thermodynamic efficiency, Oscillatory Ca2+ concentration, ATP synthesis

Rieu M, Krutyholowa R, Taylor NMI and Berry RM (2022) A new class of biological ion-driven rotary molecular motors with 5:2 symmetry. Front. Microbiol. 13:948383. doi: 10.3389/fmicb.2022.948383

• Keywords: Bacterial Flagellar Motor, Biophysical Microbiology, Protein Complexes, Rotary Molecular Motors, cryo EM, Torque, Thermodynamics of coiled coils

Mechanistic model for production of recombinant adeno-associated virus via triple transfection of HEK293 cells. Cell Press. doi: https://doi.org/10.1016/j.omtm.2021.04.006

• Keywords: rAAV viral vectors, Cell and Gene Therapy, Triple Transfection, Rep Protein, Viral DNA packaging, Biomanufacturing

Wu, S., Hong, L., Wang, Y., Yu, J., Yang, J., Yang, J., Zhang, H., & Perrett, S. (2020). Kinetics of the conformational cycle of Hsp70 reveals the importance of the dynamic and heterogeneous nature of Hsp70 for its function. Proceedings of the National Academy of Sciences, 117(14), 7814–7823. https://doi.org/10.1073/pnas.1914376117

• Keywords: Heat shock protein 70 kDa (Hsp70), Biophysics and Computational Biology, Cochaperone HSp40, Hsp70 ATPase, Conformational Dynamics, Chaperone Machinery, Protein Folding, Dimerization, Basal ATP Hydrolysis

Yousefi, O. S., Günther, M., Hörner, M., Chalupsky, J., Wess, M., Brandl, S. M., Smith, R. W., Fleck, C., Kunkel, T., Zurbriggen, M. D., Höfer, T., Weber, W., & Schamel, W. W. (2019). Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor. ELife, 8, e42475. https://doi.org/10.7554/eLife.42475

• Keywords: T cell receptor (TCR), Kinetic proofreading (KPR), Immunology and Inflammation, Optogenetic control, Phytochrome B (PhyB) ligand